Welcome to GPSAdb2.0

Genetic Perturbation Similarity Analysis

Browse

6245 datasets to explore

Query

Query by single gene/gene set

BioTrigger

Find triggers of all gene sets

fastGPSA

Enrich analysis with your interested genes

Download

Download all data easily

About

More information


Browse and explore


Browse datasets easily

The Browse tool provides easy exploration of all 6245 datasets in GPSAdb.
All datasets in GPSAdb contain pre-calculated results focused on gene perturbation.
Users can filter data using perturbation gene, cell line, and perturbation method.
Click on rows to select different datasets.

Explore in multiple ways

If users are interested in a specific dataset in GPSAdb,
simply click on the rows in the gpsaMetadata panel to select the dataset.

1. diffTable panel
The diffTable panel displays differential results using the MA plot and Volcano plot, along with additional visual representations for each target gene's differential analysis.

2. GSEA panel
We have pre-calculated the GSEA analysis for 8 categories of gene sets, allowing users to directly access the results without needing to perform any calculations.

3. fastGPSA panel
The fast GPSA tool provides more effective information for perturbed transcriptomes. Each dataset in the database supports fastGPSA analysis. By clicking on the fastGPSA page, you can download the data and then upload it on the fastGPSA analysis page..

gpsaMetadata(Search and click to select whatever interested)



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gene/gene set trans-query


ALL starts from a single gene:

The tool Query will find out which gene regulates your gene from 6245 gene knock out RNAseq datasets.
Just enter one gene below,
Click rows shown right to explore diffrent regulators
As all those 6245 datasets in GPSAdb were performed GSEA with eight source of gene sets,
trans-query of which gene regulates a specific gene sets is also supported.

gpsaMetadata(Search and click to select whatever interested)



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Step1: genes you interested


List of Genes:


Upload a one column file:

Step2: Click Run and Wait

Before you start:

Just input a list of your interested genes,clik run and wait
It takes about 20s to finish.
Please Wait
Do not leave

Step1:all genes with rank variable


List of Genes and logFC:


Upload a two column file:

Step2: Click Run and Wait

Before you start:

Please provide data similar to that required for GSEA analysis. We expect the results of differential analysis, which should consist of at least two columns: the first column for genes and the second column for logFC.

The analysis will take approximately 30-60 seconds to complete, so please be patient.

During this time, feel free to explore other features of the website; you can use other functionalities without interruption while the analysis is running.

This process is designed to be quick and efficient.

Data of GPSAdb2.0

Detailed metadata, Cell annatation file.

Individual Download of GPSAdb Database Data

Download specific datasets from the GPSAdb database individually.